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automated bioreactor

A novel automated bioreactor for scalable process – PubMed Oct 31, 2012 · We have demonstrated the potential of a new, automated, 24×15 mL replicate suspension bioreactor system, with onli...
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A novel automated bioreactor for scalable process - PubMed

Oct 31, 2012 · We have demonstrated the potential of a new, automated, 24×15 mL replicate suspension bioreactor system, with online monitoring and control, to develop an HSC proliferation and differentiation process for erythroid committed cells (CD71(+), CD235a(+)).

Automated Sampling Systems and Bioreactor Sampling by Flownamics

Automated Sampling Systems / Bioreactor Sampling Literature. Seg-Flow. Contact Us. Optimal Biotech Group. 131 Industrial Road Unit 7 Belmont, CA 94002. Phone: (650

Ambr® 250 high throughput - Multi-Parallel Bioreactor | Sartorius

The Ambr ® 250 system is a high throughput, automated bioreactor system for process development with 12 or 24 fully featured single-use 100 – 250 mL mini bioreactors. It has a wide range of applications in: Process development and process optimization. Scale-down studies. Cell culture and microbial fermentation.

Automated Bioreactor Sampling – Process Trigger Sampling for

Yeast program have implemented automated processes, including the use of an integrated parallel bioreactor system and automated bioreactor sampling system, to conduct experiments for optimizing yeast strain characterization and selection. Materials and Incorporating tools such as parallel bioreactor systems

An automated 3D-printed perfusion bioreactor combinable with

Aug 16, 2022 · In this study, an automated uni-/bi-directional perfusion bioreactor combinable with pulsed electromagnetic field (PEMF) stimulation for culturing 3D bone tissue models is proposed.

Bioreactor control systems in the biopharmaceutical industry

Aug 5, 2021 · Brief overview of bioreactor control systems. Maintaining optimal process conditions for achieving target yields and titers regardless of the bioreactor configuration, nature of the biocatalysts used, and the process disturbances are the essential function of any bioprocess control system.

Recent Advances in the Development of Bioreactors for

Dec 15, 2022 · In recent years, the development of automated and semi-automated bioreactor systems has advanced rapidly to enhance the affordability, efficacy, and quality of various cell products. Expanding the scope of available technological solutions will allow for the manufacturing of a wide range of therapeutic cell products, including CAR-T cells, TILs

MilliporeSigma Announces Acquisition of MAST® Platform from

Apr 5, 2022 · The MAST ® platform is an automated, aseptic bioreactor sampling system designed to advance bioprocessing capabilities for more efficient and cost-effective drug manufacturing. The MAST

Large-scale smart bioreactor with fully integrated wireless

Feb 14, 2024 · Traditional single-use cell-bag bioreactors, limited by their rigid and single-point sensors, struggle with accuracy and scalability for high-quality cell manufacturing. Here, we introduce a smart bioreactor system that enables multi-spatial sensing for real-time, wireless culture monitoring.

Multi-Parallel Bioreactors | Sartorius

Ambr ® 250 High Throughput, an automated bioreactor system, has 12 or 24 fully featured single-use 100 – 250 mL mini bioreactors. Speed up process development, process optimization and scale-down studies. Choose from different vessel configurations for either mammalian or microbial culture

GMP-compliant manufacturing in a closed-system automated

The use of automated bioreactors for cell expansion is a straightforward solution to tackle these manufacturing issues, and it brings several advantages, including the possibility to expand the cells in closed systems in Grade D areas, process standardization, as well as the reduction of labor required for these operations and the opportunity

Quantum: Automated Cell Culture - Terumo BCT

Quantum Cell Expansion System is an automated platform designed to simplify the open, labor-intensive tasks associated with manual cell culture.

Single-Use Bioreactors for Human Pluripotent and Adult Stem

May 17, 2021 · The authors also estimated how operating these bioreactors under automated perfusion, besides allowing a closed process and ensuring sterility, could lead to a substantial increase in cell yield per spent medium—from 4.2 × 10 5 cells/mL in six-well plates to 1.5 × 10 6 cells/mL in 1 L perfusion bioreactors .

Enhancing bioreactor arrays for automated measurements and

Jun 11, 2022 · We report the development of ReacSight, a strategy to enhance multi-bioreactor setups with automated measurements and reactive experiment control.

Recent advances in fed-batch microscale bioreactor design

Mar 1, 2022 · Integrated robotic Mini bioreactor platform for automated, parallel microbial cultivation with online data handling and process control SLAS Technol. , 24 ( 2019 ) , pp. 569 - 582 , 10.1177/2472630319860775

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